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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH8A1
All Species:
30.91
Human Site:
S298
Identified Species:
61.82
UniProt:
Q9H2A2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2A2
NP_072090.1
487
53401
S298
S
R
I
F
V
Q
K
S
I
Y
S
E
F
L
K
Chimpanzee
Pan troglodytes
XP_001170111
490
53679
S301
S
R
I
F
V
Q
K
S
I
Y
S
E
F
L
K
Rhesus Macaque
Macaca mulatta
XP_001101362
515
55911
S326
S
R
I
F
V
Q
K
S
I
Y
T
E
F
L
K
Dog
Lupus familis
XP_533415
487
53149
S298
S
R
I
F
V
Q
R
S
I
Y
E
E
F
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH00
487
53645
S298
S
R
I
F
V
Q
R
S
I
Y
S
E
F
L
K
Rat
Rattus norvegicus
P13601
501
54541
V311
V
A
A
S
R
L
F
V
E
E
S
I
Y
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509667
487
53578
S298
S
R
I
F
V
Q
R
S
I
Y
K
D
F
L
K
Chicken
Gallus gallus
P27463
509
55791
V319
I
A
G
S
R
I
F
V
E
E
P
I
Y
D
E
Frog
Xenopus laevis
Q6GNL7
902
99964
S718
G
R
L
F
L
E
E
S
I
H
D
E
F
V
K
Zebra Danio
Brachydanio rerio
Q66I21
487
53336
S298
S
R
I
F
V
E
R
S
V
Y
P
E
F
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509203
506
55370
P317
S
R
L
F
V
Q
K
P
I
F
A
D
F
V
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56YU0
501
54342
S306
G
E
I
C
V
A
S
S
R
V
F
V
Q
E
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
86
87.2
N.A.
89.9
38.3
N.A.
80.6
38.3
23.7
74.1
N.A.
N.A.
N.A.
49.4
N.A.
Protein Similarity:
100
94.2
89.1
95
N.A.
95.4
56.8
N.A.
90.3
55.5
36.5
87.6
N.A.
N.A.
N.A.
67.1
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
93.3
6.6
N.A.
80
0
46.6
66.6
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
20
N.A.
93.3
13.3
86.6
86.6
N.A.
N.A.
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
0
9
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
17
0
17
0
% D
% Glu:
0
9
0
0
0
17
9
0
17
17
9
59
0
9
25
% E
% Phe:
0
0
0
75
0
0
17
0
0
9
9
0
75
0
0
% F
% Gly:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
67
0
0
9
0
0
67
0
0
17
0
0
0
% I
% Lys:
0
0
0
0
0
0
34
0
0
0
9
0
0
0
59
% K
% Leu:
0
0
17
0
9
9
0
0
0
0
0
0
0
59
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
17
0
0
0
0
% P
% Gln:
0
0
0
0
0
59
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
75
0
0
17
0
34
0
9
0
0
0
0
0
0
% R
% Ser:
67
0
0
17
0
0
9
75
0
0
34
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% T
% Val:
9
0
0
0
75
0
0
17
9
9
0
9
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
59
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _